Mu mushinga w’ibanga wa Leta ya Amerika, itsinda ry’udusimba duto—meerschweinchen (guinea pigs), umusazi w’imbeba, n’udusazi—riba ryaratojwe nk’abajyanama b’iperereza. Bayobowe na Darwin, intwari y’umutima, bafatanya na Blaster, umuhanga mu ntwaro, na Juarez, umunyamaboko w’umukino wa karate. Speckles, umusazi w’imbeba, ni we ushinzwe ikoranabuhanga, naho Mooch, udusazi, ni abagenzuzi b’ikirere.

Iri tsinda rihabwa ubutumwa bwo kwinjira mu ruganda rwa Saber Industries, aho umuherwe mubi Leonard Saber ategura umugambi wo guhindura ibikoresho byo mu rugo (nk’imashini y’ikawa, frigo, na microwave) mu ntwaro zica abantu. G-Force igomba guhagarika uwo mugambi witwa Clusterstorm, mbere y’uko isi yose isenyuka.

Mu rugendo rwabo, bahura n’imbogamizi nyinshi—gufungwa, gutandukanywa, no guhura n’inyamaswa zidasanzwe—ariko ubucuti, ubutwari, n’ubwenge bwabo bibafasha guhangana n’akaga.